Newer Oral Levothyroxine Formulations: Is It Time to Switch Over?
نویسندگان
چکیده
Primary hypothyroidism is a frequent presentation in primary care, and treated with levothyroxine sodium tablets once daily the morning fasting state. With an adequate dose, goal to achieve thyroid stimulating hormone normal range 6–8 weeks. Medications, foods, gastrointestinal conditions can interfere absorption of tablet. This lead increased visits laboratory physician, necessitating dosage changes, causing suboptimal care. The newly-introduced oral solutions soft gel capsule formulations received approval for use by regulatory authorities. article describes kinetics levothyroxine, examines available evidence from literature, summarises rightful place solution perspective clinical practitioner. At end analysis, it evident that more robust trials this new formulation are needed consider switchover tablet form millions patients, order justify cost. newer may have role selected patients resistant hypothyroidism.
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ژورنال
عنوان ژورنال: European Medical Journal Diabetes
سال: 2023
ISSN: ['2054-6181']
DOI: https://doi.org/10.33590/emj/10306765